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Source: Computational Materials Science, Volume 267

Negative net migration hasn’t definitively happened in the U.S. for almost a century, not since the Great Depression. The U.S. native-born population is also in free fall, well below the replacement rate needed to maintain population numbers in the long run. With fewer immigrant arrivals already dealing a blow to the workforce, the shrinkage of the American taxpayer base is set to further widen the country’s deficit and hurt its prospects for economic growth.

Anthropic,这一点在safew官方版本下载中也有详细论述

Not every modern human has the same set of Neanderthal DNA, however; different people will, by chance, have inherited different fragments. But there are also some areas, termed "Neanderthal deserts," where none of the Neanderthal DNA seems to have persisted. Notably, the largest Neanderthal desert is the entire X chromosome, raising questions about whether this reflects the evolutionary fitness of genes there or mating preferences.

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